Albendazol

Albendazol

Albendazol CAS:54965-21-8

Albendazol Chemical Properties

MF: C12H15N3O2S

MW: 265,33

EINECS: 259-414-7

Punct de topire: 208-210 ° c

Densitate: 1.2561 (estimare brută)

Indicele de refracție: 1.6740 (estimare)

Solubilitate practic insolubilă în apă, liber solubilă în acid formic anhidru, foarte puțin solubilă în clorură de metilen, practic insolubilă în etanol (96%).

Pka: 10,72 ± 0,10 (estimat)

Solubilitate în apă: 0,75mg / L (209ºC)

Albendazol CAS:54965-21-8 Specificație:

Albendazol CAS:54965-21-8 Introduction:

1. Albendazol is a kind of broad spectrum thiabendazole class anthelmintics which can be applied by both human and animal.

2. Albendazol can inhibit the parasite growth and reproduction by inhibiting the intestinal and absorbing the intracellular protein, resulting in the failure of parasite in sugar uptake which is indispensable for their survival, thus causing the endogenous glycogen depletion of insects and further inhibiting fumarate reductase system, preventing the generation of adenosine triphosphate, causing that the parasites are not be able to further survive and reproduce, and ultimately die due to energy depletion.

Albendazol CAS:54965-21-8 Functions

Albendazol is an anthelmintic or anti- worm medication. It prevents newly hatched insect larvae (worms) from growing or multiplying in your body.  

Albendazol is used to treat certain infections caused by worms such as pork tapeworm and dog tapeworm.

1. Albendazol is highly effective broad spectrum anthelmintic drugs, is benzimidazole deworming drugs in the broader spectrum.

2. Albendazol is highly active against nematodes, schistosomes, tapeworms, but also significantly inhibited the development of eggs.

3. Albendazol on parasitic nematodes in a variety of animals, schistosomes, tapeworms and cysticerci also has a significant role in repelling.

4. Albendazol is applied to get rid of roundworm, pinworm, hookworm, whipworm, can also be used for deworming livestock.

Albendazol CAS:54965-21-8 Application:

1. Antiparazitar cu spectru larg; Folosit pentru a expulza nematodele, teniile, viermii trematode și ectoparaziții la animale.

2. Albendazol has a broad spectrum of insect repellents, and has a strong effect on nematode, tapeworm and trematode; Its mechanism of action is to bind to microtubulin in the worm and prevent it polymerize withα-tubulin to form microtubules, thus affecting cell reproduction processes such as mitosis, protein assembly and energy metabolism.

3. Ivermectina are un efect bun asupra paraziților interni și externi, în special a insectelor artropode și a viermilor nematodi interni; Este utilizat în principal pentru a expulza nematodiaza gastro-intestinală, viermi pulmonari și ectoparaziți; Mecanismul deparazitării este de a promova eliberarea GABA de către neuronii presinaptici, deschizând astfel canalele ionice de clorură mediate de GABA; Fluxul de ioni de clor poate reduce rezistența membranei celulare, poate provoca o ușoară depolarizare a potențialului static al membranei postsinaptice, poate interfera cu transmiterea semnalului între mușchii nervoși și, de asemenea, poate determina relaxarea și paralizarea corpului insectelor, rezultând moartea sau expulzarea corpul insectelor.